What day is the match?
This Friday night. Put a big red circle in your diary around September 16.
What time does it start?
It's an evening kick-off. 8pm.
What TV channel is it on?
Sky Sports 1. And because it's the weekend's big'un, there's plenty of build-up. Sky's coverage begins at 6.30pm.
Alternatively, if you don't have Sky, you can follow all the live action right here when this very page turns into our live match commentary.
What can we expect?
The touchline action could be as explosive as that on the pitch at Stamford Bridge when Jurgen Klopp goes head-to-head with Antonio Conte.
Both managers are renowned for the remarkable intensity of their touchline antics and the fourth official is likely to have a job on his hands maintaining order in the two technical areas.
Last season's corresponding fixture, in late October, saw Klopp pull off the first eye-catching result of his nascent Liverpool tenure as the visitors recorded an impressive 3-1 win.
If the teams' last encounter, in a pre-season friendly in the United States, is anything to go by, Friday's game beneath the floodlights could be a spicy affair.
Chelsea midfielder Cesc Fabregas was sent off for an ugly foul on Ragnar Klavan, while Liverpool's Marko Grujic had to go to hospital following a clash of heads with Bertrand Traore.
It could also be spectacular. The two teams average more shots on goal per game than any other sides in the division, while Liverpool's players have covered more distance than any other team.
After defeat at Burnley and a 1-1 draw at Tottenham, Liverpool returned to winning ways last weekend with a clinical 4-1 thrashing of champions Leicester City at the newly-expanded Anfield.
Chelsea saw their perfect start to the campaign ended by a 2-2 draw at Swansea City in which they went 1-0 up, fell 2-1 down and then rescued a point through Diego Costa's acrobatic 81st-minute equaliser.
The way Chelsea let Swansea back into the match suggested the vulnerability that plagued them last season, when they finished 10th, continues to hover below the surface.
Croatian centre-back Dejan Lovren is due to return for Liverpool, following a head injury, in place of Lucas Leiva, whose error against Leicester gift-wrapped a goal for Jamie Vardy. But Germany midfielder Emre Can remains absent with an ankle injury.
David Luiz is expected to make his second debut for Chelsea, five years and seven months after his first appearance for the club, which coincidentally came in a home game against Liverpool.
The Brazil centre-back, 29, returned to Chelsea from Paris Saint-Germain on transfer deadline day for a reported fee of £32 million.
Luiz, previously a Chelsea player between 2011 and 2014, is likely to replace captain John Terry, who has been ruled out for 10 days with ankle ligament damage sustained at Swansea.
What are they saying?
Klopp on Chelsea
"I know about our respect for Chelsea and I am pretty sure from the other side there is exactly the same.
"They've seen us playing and they know we are not easy to play and that is what I thought most about in the last two days and what I will think about because there is always a way to create moments which you are not expecting.
"The problem is they maybe have the same plan. They were champions two years ago and then had a difficult year and they changed their manager. Last season was not a Chelsea season and now they are back on track, so we need to be ready for a real challenge."
What are the odds?